| Time CDT | |||
| 08/31 | South Alabama | W 35 - 21 | |
| 09/07 | @ Colorado | L 31 - 34 OT | |
| 09/14 | Northern Illinois | W 44 - 8 | |
| 09/21 | @ Illinois | W 42 - 38 | |
| 09/28 | Ohio State | L 7 - 48 | |
| 10/05 | Northwestern | W 13 - 10 | |
| 10/12 | @ Minnesota | L 7 - 34 | |
| 10/19 | Bye | ||
| 10/26 | Indiana | L 31 - 38 | |
| 11/02 | @ Purdue | L 27 - 31 | |
| 11/09 | Bye | ||
| 11/16 | Wisconsin | L 21 - 37 | |
| 11/23 | @ Maryland | W 54 - 7 | |
| 11/29 Friday | Iowa | L 24 - 27 | |